A PhD student in ILS must have a Supervisor who is committed to instruct the thesis work and contribute to ILS curriculum. The PI’s who have given their contact information are listed below categorized roughly within the research areas represented in ILS. The list is non-exclusive and updated regularly.
All PIs affiliated in the University of Helsinki can supervise the students’ thesis work in ILS provided that the thesis project falls within the integrative life science research areas. A prospective student should agree with his/her PhD thesis project supervision with a PI prior to applying to ILS.
Jump to: Proteomics and Metabolomics - Genetics and Genomics - Developmental Biology and Physiology - Cell and Molecular Biology - Bioinformatics and Systems Biology - Biochemistry, Biophysics and Structural Biology
Note: the ILS research areas are not limited to the ones indicated here and new areas are strongly encouraged!
Pathophysiology of Misfolding disorders, Clinical Proteomics and Systems Proteomics, Nanobiology
Cell Signalling Networks in Activation of Innate Immunity
Systems Biology of the human kinases and transcription factors
Genetics and genomics of reproductive diseases including also stillbirth and malformations
Genomics, functional genomics and metagenomics of prokaryotes and eukaryotes
Natural variation and plant stress responses
Natural product discovery from bacteria using a combination of genomics and analytical chemistry.
Nutrient sensing mechanisms and their role in the control of energy metabolism and growth
Genetic and neurobiological basis of anxiety disorders using mouse and human genomic approaces
Genetics of common obstetric disorders
Comparative animal genomics
Minna Katariina Nyström
Cancer genetics and epigenetics
Genetics and genomics of plant-pathogen interactions, plant innate immunity
Epigenetic and genetic basis of common human cancers using hereditary cancer syndromes as a shortcut
Genomics and transcriptomics of host-pathogen interactions between bacteria and plants.
Genetics and evolution of viruses
Statistical genetics, biostatistics, bioinformatics, genetic epidemiology
Genetics of human immune disorders
Genetics and immunopathogenesis of chronic inflammatory diseases
Retrotransposon-driven plant genome and epigenome dynamics; genomics of plant traits
Genetics and molecular mechanisms of translation diseases
Developmental Biology and Physiology
Finding New Ways For Neuroprotection and Neurorestoration: Focus On Stroke and Parkinson's Disease
Development of a method opposite to gene knock out-studies on effects of elevating endogenous genes
Craniofacial Morphogenesis and Tissue Regeneration in non-mammalian vertebrates
Retinal mechanisms underlying basic aspects of visual performance in humans and other animals
Plant developmental biology, flower and inflorescence development, plant biotechnology
Neurotrophic factors in Drosophila
Normal development and developmental disorders in domestic animals
Plant cell wall biosynthesis with special emphasis on lignin biosynthesis
Molecular and cellular mechanisms of renal differentiation
Signaling mechanisms guiding functional maturation of glutamatergic synapses in the brain
Ari Pekka Mähönen
Cambium development in Arabidopsis thaliana root
Maturation and differentiation of dental and corneal stem cells
Molecular and cellular regulation of epithelial morphogenesis using mouse as a model
Genetic control of neuronal differentiation in the developing brain.
We study structure, biology and therapeutic potential of neurotrophic factor proteins
I develop theories and models about the interdependence between development and the evolution.
Inductive signalling in kidney morphogenesis, disruption of developmental, disease mechanisms
Spatiotemporal regulation of signaling molecules and tissue morphogenesis
Molecular mechanisms of sleep
Development and regeneration of teeth
Molecular and ionic mechanisms of neuronal signaling, ionic plasticity mechanisms, electrophysiology
Cell biology and molecular mechanisms of RNA virus replication.
Our focus is on determination of molecular mechanisms used by phytopathogenic fungi to cause disease
We investigate the mechanisms coordinating mitochondrial homeostasis and their role in human disease
Biogenesis and maturation of autophagosomes. Functions of lysosomal membrane proteins.
Leukocyte adhesion in health and disease
Regulation of gene expression by pre-mRNA splicing. Genomics related to gene expression regulation.
Identification of genes/proteins involved in the invasion and metastasis of human melanomas
Molecular mechanisms of neurodegenerative diseases, focus on Alzheimer's and Parkinson's diseases.
Mitochondrial metabolism and disease
Endoplasmic reticulum structure and dynamics
Modulators of immune responses
Stem cells and aging
Immune evasion in malaria: surface variant antigens, host-parasite and host-vector interaction
Breast Cancer Signalling Pathways and Therapeutic Intervention
orexins (including drug discovery, diagnostics etc.), G-protein-coupled receptors, lipid signaling
DNA repair-related mechanisms of breast cancer.
Pekka Juhani Lappalainen
Regulation of actin and plasma membrane dynamics in animal cells
Pathophysiological mechanisms of diabetic nephropathy
Growth factor signaling with focus on ER stress pathways and mitochondria dynamics in human disease.
Kinase signaling linking metabolism and growth
Kristiina Maria Mäkinen
Molecular mechanisms underlying Potato virus A infection.
Genetics, pathomechanisms and targeted therapy of hematological malignancies and immunology
Molecular mechanisms of cancer development and lymphatic reprogramming
Role of nutrients in the development of colorectal cancer
Structure and function of prokaryotic viruses.
Prptein interactions in virus-host interplay
Molecular microbiology, virulence factors, bacteriophages and phage therapy
Bioassay development and screening in drug discovery
Virology, molecular mechanisms of defence against pathogens in plants
Roles of actin fibers in regulating E-cadherin and integrin based adhesions
Zoonotic viruses: molecular epidemiology, pathogenesis, diagnostics and disease associations
Maria Kristina Vartiainen
Actin as an organizer of gene expression: actin in transcriptional regulation and nuclear actin
Cancer biology, Translational biology, Models of cancer
Not more than 100 characters including spaces. Anything exceeding this will be omitted
Molecular bacteria-host interactions
Bioinformatics and Systems Biology
Computational systems medicine
Computational method development and applications to biomedical and clinical data
Probabilistic modelling for bioinformatics and computational systems biology, RNA-seq, metagenomics
Functional lipidomics - from cells to body and from species to ecosystems
Computational sequence analysis and methods development
Algorithmic bioinformatics for high-throughput sequencing applications
Computational models of gene regulation; biological sequence analysis; de novo sequencing
Biochemistry, Biophysics and Structural Biology
How the viral universe is constructed
Visualizing virology and nanotechnology
Polysialic acid and its regulation in neuroblastoma cells
The group works on leukocyte and neuronal adhesion i.e. integrin signaling and generation of memory.
The structure, function and mechanism of cell-integral and associated systems.
Emerging human viruses - pathogenesis and innovative diagnosis
Protein Splicing and Related phenomena for Protein Engineering
Structural biology and function of neuronal receptors and adhesion proteins.
Molecular details of prokaryotic viruses
Probing co-translational protein secretion with small-molecu...
Application of NMR spectroscopy for studying structure, dynamics and interactions of biomolecules
Replication complexes of dsRNA viruses