List of Participating Graduate Students
- with poster information

Bioinformatics and Systems Biology - Cancer Biology - Cell & Molecular Biology - Genetics - Immunology - Neuroscience - Nutrition - Plants - Structural Biology and Biophysics - Virology and Microbiology

Bioinformatics and Systems Biology

Cesar Araujo
University of Oulu
 Prostatic Acid Phosphatase (PAP) and Cholesterol Binding (tentative title)

Andrey Golubtsov
University of Helsinki
 The glycine specificity motif in cysteine proteases
 A. Golubtsov and T. Ahola

Anna Huhtinen
University of Turku
 Generation and characterization of a stable vascular smooth muscle cell population expressing the human alpha2B-adrenoceptor
 Huhtinen, A., Vainio, M. and Scheinin, M.

Janita Thusberg
University of Tampere
 EXPLORING PROTEIN STRUCTURE-FUNCTION RELATIONSHIPS BY ANALYSING AMINO ACID SUBSTITUTIONS AT THE SEQUENCE AND STRUCTURAL LEVEL
 Janita Thusberg and Mauno Vihinen

Mikko Vainio
Åbo Academi
 Generating conformer ensembles using a genetic algorithm
 Mikko J. Vainio and Mark S. Johnson

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Cancer Biology

Emma-Leena Alarmo
University of Tampere
 A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7
 Emma-Leena Alarmo, Tuula Kuukasjärvi, Ritva Karhu, Anne Kallioniemi

Reetta Ässämäki
University of Helsinki
 Developments in the screening and characterization of CTCL-associated gene aberrations by modern biological methods, including microarray, moleculocytogenetics and immunohistology.
 Karenko L, Hahtola S, Ässämäki R, Zhou Y, Carlsson E, Ranki R

Emilia Carlsson
University of Helsinki
 EXPRESSION PROFILING OF THE NAV3 PROTEIN, DELETED/TRANSLOCATED IN COMMON FORMS OF CUTANEOUS T-CELL LYMPHOMAS
 Emilia Carlsson, Valtteri Häyry, Ying Zhou, Leena Karenko, Ismo Virtanen, Tapio Visakorpi, Kai Krohn, Annamari Ranki

Mira Heinonen
University of Helsinki
 The prognostic role of HuR in breast cancer
 Mira Heinonen, Rainer Fagerholm, Hannaleena Eerola, Outi Kilpivaara, Caj Haglund, Heli Nevanlinna and Ari Ristimäki

Riina Kuuselo
University of Tampere
 The recurrent 19q13 amplification in pancreatic cancer harbors putative new drug targets
 Riina Kuuselo, Kimmo Savinainen, David O. Azorsa, Gargi D. Basu, Ritva Karhu, Sukru Tuzmen, Spyro Mousses, and Anne Kallioniemi

Henna Mattila
University of Tampere
 Characterization of the Finnish prostate cancer susceptibility locus HPCX
 Henna Mattila, Maija Wolf, Kim Chang Sik, Mauno Vihinen, Teuvo Tammela, Olli Kallioniemi, Outi Monni, Tarja Ikonen and Johanna Schleutker

Jenita Pärssinen
University of Tampere
 Gene expression profiling of the 17q23 amplicon in breast cancer

Sirkku Pollari
University of Turku
 RNA interference profiles, gene expression and copy number changes in bone metastatic breast cancer cells:
an integrated molecular and functional screening
 Sirkku Pollari, Merja Perälä, Saija Haapa-Paananen, Kirsi Ojala, Niko Sahlberg, Maija Wolf, Henrik Edgren, Pekka Tiikkainen, Sanna-Maria Käkönen, Olli Kallioniemi

Ileana Quintero
University of Oulu
 Localization of PAP in human prostate cancer tissue

Sanna Siltanen
University of Tampere
 ARLTS1/ARL11 germ line variants and the risk for breast, prostate and colorectal cancer
 Sanna Siltanen,Kirsi Syrjäkoski,Rainer Fagerholm,Tarja Ikonen,Kaija Holli,Teuvo Tammela,Heikki J Järvinen,
Jukka-Pekka Mecklin,Heli Nevanlinna,Lauri A Aaltonen,Johanna Schleutker,Pia Vahteristo

Alexandra Thiel
University of Helsinki
 Expression of cyclooxygenase-2 is regulated by GSK-3beta in gastric cancer
 Alexandra Thiel, Mira Heinonen, Johanna Rintahaka, Tuija Hallikainen, Annabrita Hemmes, Dan A. Dixon, Caj Haglund and Ari Ristimäki

Soile Tuomela
University of Turku
 Th1 Response and Cytotoxicity Genes Are Down-Regulated in Cutaneous T-Cell Lymphoma
 Hahtola S., Tuomela S., Elo L., Häkkinen T., Karenko L., Nedoszytko B., Heikkilä H., Saarialho-Kere U., Roszkiewicz J., Aittokallio T., Lahesmaa R. and Ranki A.

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Cell & Molecular Biology

Malin Åkerfelt
Åbo Academi
 Identification of novel target genes for HSF2 in testis with ChIP-on-chip strategy
 Malin Åkerfelt, Eva Henriksson, Asta Laiho, Stephen Rudd and Lea Sistonen

Jessica Alm
University of Turku
 OPTIMIZATION OF CULTURE CONDITIONS FOR DIFFERENTIATION OF ADULT BONE MARROW DERIVED HUMAN MESENCHYMAL STEM CELLS INTO FUNCTIONAL OSTEOBLASTS IN VITRO
 Jessica J Alm, Teuvo A Hentunen ,Kalervo H Väänänen,Hannu T
Aro

Julius Anckar
Åbo Academi
 Specificity determinants in SUMO-mediated negative regulation of heat shock factors
 Julius Anckar, Ville Hietakangas, Henri A. Blomster, Konstantin Denessiouk, Mitsuaki Fujimoto, Dennis J. Thiele, Mark S. Johnson, Akira Nakai & Lea Sistonen

Susann Björk
University of Turku
 New insights into alpha2C-adrenoceptor trafficking
 Susann M. Björk, Carl M. Hurt, Brian Kobilka, Timothy Angelotti

Mirkka Heikonen
University of Turku
 Expression of RAB genes in bone resorbing human osteoclasts
 M. Heikonen, K.G. Büki, H. Vuorikoski, J. Vääräniemi, H.K. Väänänen

Satu Helppolainen
University of Tampere
 Rhizavidin – A New Member of the Avidin Family
 Satu H. Helppolainen, Kirsi P. Nurminen, Juha A.E. Määttä, Tiina Paldanius,
Markku S. Kulomaa and Henri R. Nordlund

Heli Honkala
University of Helsinki
 From gene to function: Molecular genetics and biology of hydrolethalus syndrome
 Heli Honkala, Kirmo Wartiovaara, Riitta Salonen, Leena Peltonen, Marjo Kestilä

Satu Kärkkäinen
University of Tampere
 Mapping the interaction of SH3 domains with PAK1 and PAK2
 S.Kärkkäinen, K. Saksela, GH. Renkema

Aura Kaunisto
University of Turku
 Specific Phosphorylation Regulates the Ubiquitylation and Rapid Turnover of c-FLIP(S)
 Aura Kaunisto, Vitaly Kochin, Minna Poukkula, Ville Hietakangas, Konstantin Denessiouk, Tuire Katajamäki, Mark S. Johnson, Lea Sistonen, and John E. Eriksson

Jaana Lehtiniemi
University of Tampere
 Do abdominal aortas contain bacterial DNA?
 Jaana Lehtiniemi, Niku Oksala, Simo Nikkari, Seppo T. Nikkari

Annina Lyly
University of Helsinki
 Molecular interactions of PPT1 - the protein defected in INCL disease
 Annina Lyly, Anu Jalanko

Juha Määttä
University of Tampere
 Properties and Use of Highly Stable Chimeric Avidin
 Juha Määttä, Vesa Hytönen, Tiina Paldanius, Henri Nordlund and Markku Kulomaa

Astrid Murumägi
University of Tampere
 Ets transcription factors Ets1, Ets2 and ESE-1 participate in the transcriptional regulation of the human AIRE gene
 Astrid Murumägi, Olli Silvennoinen and Pärt Peterson

Mirja Nurmio
University of Turku
 The tyrosine kinase inhibitor imatinib mesylate perturbs postnatal testicular development in the rat
 Mirja Nurmio, Jorma Toppari, Farasat Zaman, Jorma Paranko, Olle Söder and Kirsi Jahnukainen

Jonas Nyman
University of Turku
 ISOLATION AND COMPARISON OF THE VACUOLAR PROTON PUMP ISOFORM A3-CONTAINING COMPARTMENTS FROM HUMAN OSTEOCLASTS AND MACROPHAGES
 Nyman J. and Väänänen H.K.

Tiina Paldanius
University of Tampere
 Towards multi-ligand avidin nanotools
 Tiina Paldanius, Vesa Hytönen, Henri Nordlund, Juha Määttä,
Markku Kulomaa and Kristiina Takkinen

Heli Pessa
University of Helsinki
 Localization of U4atac and U6atac snRNAs in mouse cell lines
 Heli K. J. Pessa, Annukka Ruokolainen, and Mikko J. Frilander

Anne Pihlajaniemi
Helsinki Univeristy of Technology
 Production of L-xylulose by xylitol-4-dehydrogenase
 Anne Pihlajaniemi, Johannes Aarnikunnas, Airi Palva, Matti Leisola and Antti Nyyssölä

Maija Puhka
University of Helsinki
 Partitioning of the Endoplasmic Reticulum During Cell Division
 Maija Puhka, Helena Vihinen and Eija Jokitalo

Johanna Rinne
University of Jyväskylä
 Internalization of novel non-viral vector TAT-Streptavidin into mammalian cells
 Rinne J., Albarran B., Jylhävä J., Ihalainen T.O., Stayton P., Kulomaa M., Vihinen-Ranta M.

Taija Saloniemi
University of Turku
 Enhanced androgen and estrogen action in human hydroxysteroid dehydrogenase (17beta) 1 expressing transgenic mice
 T. saloniemi, T. Lamminen, K. Huhtinen, H. Kujari, M. Poutanen

Outi Sareila
University of Tampere
 Orazipone decreases inducible nitric oxide synthase expression and nitric oxide production in activated macrophages
 Outi Sareila, Mari Hämäläinen, Hannu Kankaanranta, Erkki Nissinen and Eeva Moilanen

Salla Suomi
University of Turku
 CHARACTERISATION OF MICRO-RNA EXPRESSION PROFILES IN MOUSE BONE AND CARTILAGE CELLS
 Suomi Salla, Taipaleenmäki Hanna, Väänänen Kalervo, Säämänen Anna-Marja, Hentunen Teuvo, Büki Kalman, Laitala-Leinonen Tiina

Heikki Turunen
University of Turku
 Identification and Functional Characterization of Epididymal Genes Using Knock-out Mice
 Anastasios E Damdimopoulos, Heikki Turunen, Jenni Jalkanen, Anton Krutskikh, Ramin Shariatmadari, Dwi Ari Pujianto, Ilpo Huhtaniemi, Matti Poutanen

Monica Yabal
University of Helsinki
 The Bcl-2 family protein N-Bak induces structural changes in Mitochondrial and ER membranes
 Monica Yabal, Eija Jokitalo, Urmas Arumäe, Marja Makarow

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Genetics

Maaria Kleemola
University of Turku
 Genome-wide expression profiling of lysinuric protein intolerance (LPI) with microarrays
 Maaria Kleemola, Johanna Salmi, Laura Tanner, Johannes Tuikkala, Olli S. Nevalainen, Olli Simell, Juha Mykkänen and Kirsi Huoponen

Sampo Sammalisto
University of Helsinki
 A Quantitative Trait Locus for Human HDL cholesterol on Chromosome 18p
 Sampo Sammalisto, Peter Almgren, Hemang Parikh, Tero Hiekkalinna, Tiinamaija Tuomi, Marju Orho-Melander, Marketa Sjögren, Marja-Riitta Taskinen, Leena Peltonen, Markus Perola and Leif Groop

Eija Siintola
University of Helsinki
 Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
 Eija Siintola, Sanna Partanen, Petter Strömme, Aleksi Haapanen, Matti Haltia, Jan Maehlen, Anna-Elina Lehesjoki and Jaana Tyynelä

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Immunology

Jukka Alinikula
University of Turku
 Regulation of plasma cell differentiation by Bcl6
 Jukka Alinikula, Laura Mustonen, Kalle-Pekka Nera, Olli Lassila

Jan-Jonas Filén
University of Turku
 DETERMINATION OF INTERLEUKIN-4 REGULATED PROTEINS IN THE MICROSOMAL FRACTION OF T HELPER CELLS BY USING ISOTOPE-CODED AFFINITY TAGS
 Jan-Jonas Filén, Sanna Filén, Robert Moulder, Petri Kouvonen, Suvi Kantola, Mikko Katajamaa, Tuula A. Nyman, and Riitta Lahesmaa

Mari Hämäläinen
University of Tampere
 Inhibition of iNOS expression and NO production by anti-inflammatory steroids - role of histone deacetylation
 Mari Hämäläinen, Riikka Lilja, Hannu Kankaanranta and Eeva Moilanen

Anu Huurre
University of Turku
 Mode of delivery – effects on gut microbiota and humoral immunity
 Huurre Anu, Kalliomäki Marko, Rautava Samuli, Rinne Minna, Salminen Seppo, Isolauri Erika

Ulla Jalonen
University of Tampere
 DOWN-REGULATION OF TRISTETRAPROLIN EXPRESSION RESULTS IN ENHANCED IL-12 AND MIP-2 PRODUCTION AND REDUCED MIP-3a SYNTHESIS IN ACTIVATED MACROPHAGES
 Jalonen Ulla, Nieminen Riina, Vuolteenaho Katriina, Kankaanranta Hannu and Moilanen Eeva

Kaisa Koskinen
University of Turku
 Developmental regulation of endothelial selectins in humans
 Kaisa Koskinen, Sirpa Jalkanen and Marko Salmi

Marika Merinen
University of Turku
 Vascular Adhesion Protein-1 Is Involved in Both Acute and Chronic Inflammation in the Mouse
 Marika Merinen, Heikki Irjala, Marko Salmi, Ilkka Jaakkola, Arno Hänninen and Sirpa Jalkanen

Nora Pöntynen
University of Helsinki
 CHARACTERIZATION OF AN Aire-DEFICIENT APS1 DISEASE MODEL
 Nora M. Pöntynen, T. Petteri Arstila, Aaro Miettinen, Olle Kämpe, Outi Vaarala, Leena Peltonen and Ismo Ulmanen

Maritta Pykäläinen
University of Turku
 NOVEL GENES AND MECHANISMS INVOLVED IN THE REGULATION OF TH CELL DIFFERENTIATION
 Maritta Pykäläinen, Riikka Lund, Tiina Naumanen, Craig Dixon, Joonas Scheinin, Zhi Chen, Helena Ahlfors, Omid Rasool & Riitta Lahesmaa

Kirsi Rautajoki
University of Turku
 IL-4 INHIBITS CASPASE-3 BY REGULATING SEVERAL PROTEINS IN THE FAS PATHWAY DURING INITIAL STAGES OF HUMAN TH2 CELL DIFFERENTIATION
 Kirsi Rautajoki1,3, Elisa Marttila1, Tuula Nyman1,2, and Riitta Lahesmaa1 1Turku Centre for Biotechnology, University of Turku and Åbo Akademi, Finland 2Institute of Occupational Health, Helsinki, F

Tiina Salonen
University of Tampere
 Inhibition of classical PKC isoenzymes down-regulates STAT1 activation and iNOS expression in macrophages
 Salonen T, Sareila O, Jalonen U, Kankaanranta H, Tuominen RK, Moilanen E

Satumarja Stenman
University of Tampere
 Production of coealiac disease autoantibodies after in vitro gluten challenge
 Stenman S., Lindfors K., Korponay-Zsabo IR., Wieser H., Lohi O., Mäki M. and Kaukinen K.

Johanna Tahvanainen
University of Turku
 Sip1, a novel Stat6 interacting protein regulates Stat6, human T helper cell differentiation and apoptosis
 Johanna Tahvanainen, Teemu Kallonen, Hanna Lähteenmäki, Eeva Rainio, Kaisa Heiskanen, Heli Putaala, Jukka Westermarck and Riitta Lahesmaa

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Neuroscience

Sébastien Duprat
University of Helsinki
 Netrin1 in the neural stem cell niche
 Sébastien Duprat, Janne Hakanen, Marjo Salminen

Jenni Eriksson
Åbo Academi
 Compartment-specific functions of JNK – a screen for neuronal death mediators
 Jenni Eriksson, Vesa Hongisto, Benny Björkblom, Christophe Bonny and Eleanor Coffey

Kristiina Huttu
University of Helsinki
 NKCC1 knock-out mice hippocampus generates GDP-activity despite of attenuated GABAergic excitation
 Kristiina Huttu, Heini Niinimäki, Sampsa Sipilä and Kai Kaila

Evgeny Kulesskiy
University of Helsinki
 Application of fluorescence resonance energy transfer (FRET) to study N-syndecan signaling on the surface of living cells
 Evgeny Kulesskiy, Sarka Tumova, Anni Hienola, Heikki Rauvala.

Mervi Kuronen
University of Helsinki
 Studying cystatin B related neurodegenerative pathways using Drosophila melanogaster
 Kuronen M, Salo P, Lehesjoki A-E, Myllykangas L

Johan Pahlberg
University of Helsinki
 Amino acid substitutions and spectral tuning in an invertebrate visual pigment
 Johan Pahlberg, Megan Porter, Keith A. Crandall and Kristian Donner

Sanna Partanen
University of Tampere
 Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
 Eija Siintola, Sanna Partanen, Petter Strömme, Aleksi Haapanen, Matti Haltia, Jan Maehlen, Anna-Elina Lehesjoki and Jaana Tyynelä

Tero Viitanen
University of Helsinki
 Mechanisms of GABAergic [K+]o transients in the rat hippocampal slice
 Viitanen T.M., Kaila, K. & Voipio, J.

Carina von Schantz
University of Helsinki
 Characterization of Cln1 and Cln5 deficient mice reveals clues to common molecular pathways in neuronal ceroid lipofuscinosis
 C von Schantz, JD Cooper , O Kopra, CC Pontikis, M Gentile, L Peltonen, A Jalanko

Nina Westerlund
Åbo Academi
 JNK1 Determines Microtubule Dynamics and Axonal Length Through SCG10
 Tararuk T., Östman N., Li W., Björkblom B., Padzik A., Zdrojewska J., Hongisto V., Herdegen T., Konopka W., Courtney M.J. and Coffey E.T.

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Nutrition

Tarja Piirainen
University of Turku
 Nutrition counseling resources of nurses in well-women (WW) and well-baby (WB) clinics in Finland
 Piirainen Tarja, Laiho Kirsi, Hoppu Ulla, Huurre A, Isolauri E

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Plants

Suvi Broholm
University of Helsinki
 GhCYC2 and flower type differentiation in Gerbera hybrida
 Suvi Broholm, Roosa Laitinen, Teemu Teeri and Paula Elomaa

Henrietta Grönberg
University of Helsinki
 Pathogenic and beneficial Rhizoctonia spp. interactions in Scots pine (Pinus sylvestris) roots
 Henrietta Grönberg, Kielo Haahtela and Robin Sen

Luis Orlando Morales
University of Joensuu
 Genetic diversity in indiginous mahoganies from Africa and America.
 Luis O Morales, Ari Pappinen and Mark Appiah

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Structural Biology and Biophysics

Jenny Björkqvist
Åbo Academi
 Differences in the domain forming properties of N-palmitoylated neutral glycosphingolipids in bilayer membranes
 Stina Maunula, Y. Jenny E. Björkqvist, J. Peter Slotte and Bodil Ramstedt

Anna-Maria Brandt
Åbo Academi
 Structural studies on the open conformation of integrin alpha1 I domain
 Anna-Maria Brandt, Anna-Brita Öst, J. Santeri Puranen, Jarmo Käpylä, Mark S. Johnson and Tiina Salminen

Elena Gorbikova
University of Helsinki
 Protolytic reactions in cytochrome c oxidase studied by means of FTIR spectroscopy
 Elena A. Gorbikova, Michael I. Verkhovsky

Anni Kauko
University of Turku
 Structural characterisation of Dps-like peroxide resistance protein (Dpr) from S. suis
 Anni Kauko, Arto Pulliainen, Sauli Haataja, Jukka Finne & Anastassios
Papageorgiou

Heidi Kidron
Åbo Academi
 Substrate specificity of human retina specific amine oxidase
 Kidron H, Airenne T, Nymalm Y, Kaitaniemi S, Grön K, Elima K, Salmi M, Jalkanen S and Salminen T

Matts Nylund
Åbo Academi
 The 4,5-trans double bond, the 3-hydroxy group and an saturated acylchain of sphingomyelin is required for maintaining the inhibiting effect on the protein mediated glycolipid transfer
 Matts Nylund, Matti A. Kjellberg, Robert Bittman and Peter Mattjus

Vimal Parkash
University of Helsinki
 Insights of
RET-domains into the GDNF-GFRalpha-Ret complex
 vimal parkash, Veli-Matti Leppänen, Adrian Goldman

Enni Penttilä
University of Helsinki
 Proliferation/differentiation balance in molar development
 Enni Penttilä, Pauliina Munne, Kathy Kavanagh, Jukka Jernvall

Santeri Puranen
Åbo Academi
 Towards accurate molecular conformation-dependent atomic charges: implementing and parameterizing an electronegativity equalization-based procedure.
 J.S. Puranen and M.S. Johnson

Susanna Repo
Åbo Academi
 Binding properties of HABA-type azo derivatives to avidin and avidin-related protein 4
 Repo S, Paldanius TA, Hytönen VP, Nyholm TKM, Halling KK, Huuskonen J, Pentikäinen OT, Rissanen K, Slotte JP, Airenne TT, Salminen TA, Kulomaa MS and Johnson MS

Annu Söderholm
Åbo Academi
 Identification of novel androgen receptor binding compounds using virtual screening
 Annu Söderholm, Tommi Nyrönen, Pekka Lehtovuori

Lenita Viitanen
Åbo Academi
 Structural studies on sterol carrier protein-2 from plants.
 Lenita Viitanen and Tiina A. Salminen

Gun West
Åbo Academi
 MEMBRANE AND ACTIVITY OF ACTIVITY THE GLYCOLIPID TRANSFER PROTEIN
 GUN WEST, MATTS NYLUND, J. PETER SLOTTE AND PETER MATTJUS

Henri Xhaard
Åbo Academi
 Structural evolution of the catecholamine-binding GPCRs
 Xhaard, H. and Johnson, M. S.

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Virology and Microbiology

Giuseppe Balistreri
University of Helsinki
 Functional defects in the replicase protein nsP2 of Semliki Forest virus temperature-sensitive mutants.
 Giuseppe Balistreri, Tero Ahola, Leevi Kääriäinen

Wilmer Cuellar
University of Helsinki
 RNA silencing suppression strategies of Sweet potato chlorotic stunt virus
 Wilmer Cuellar, Jari Valkonen

Miia Helanto
Helsinki Univeristy of Technology
 Characterization of genes involved in fructose utilization by Lactobacillus fermentum
 Miia Helanto, Johannes Aarnikunnas, Airi Palva, Matti Leisola and Antti Nyyssölä

Elina Hienonen
University of Helsinki
 Stabilization of heterologous transcripts with hrpA, mRNA of a type III secretion system component
 Elina Hienonen, Martin Romantschuk, Suvi Taira

chunmei Li
University of Helsinki
 Structural and Functional Analysis of HrpZ Harpin
of Pseudomonas syringae
 Minna Haapalainen & Chun-Mei Li

Justus Reunanen
University of Helsinki
 Shelf-life of nisin in intestinal environment
 Justus Reunanen and Per Saris

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